@ ashvio: The BoS makes the constellation statues start appearing. When you find all 12 of those, you get infinite

and the potions start appearing. When you find all 12 of those, you will have up-kick. (I believe all this information is in the Items, Quests, & Families Thread.)
@ The Dojo: It's a little cruel that they make the first level the hardest one. I tried it two or three times shortly after I started playing, and have never gotten past that first level. Now I refuse to enter any PD that unlocks coef.5's until I find the BoS.